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grade 3 meningioma
Grade 3 meningioma
A grade 3 meningioma, also called an anaplastic or malignant meningioma, is a rare and aggressive type of brain tumor that arises from the meninges—the protective membranes surrounding the brain and spinal cord.
⚠️ Key Features:
Highly aggressive and fast-growing
Often invades nearby brain tissue
High recurrence rate, even after treatment
Can arise de novo or evolve from a lower-grade meningioma (grade 1 or 2)
Classified as WHO grade 3, the most severe form
🧬 Histological Characteristics:
High mitotic index (rapid cell division)
Cellular atypia and pleomorphism (abnormal-looking cells)
Necrosis may be present
Brain invasion is common

Grade 3 Meningioma
Quick Summary Table:
Feature
Details
WHO Grade
Grade 3 (Anaplastic/Malignant)
Growth Behavior
Rapid, infiltrative, often recurrent
Treatment
Surgery + mandatory radiotherapy
Recurrence
Very likely, even after complete removal
Prognosis
Poor to guarded